Desktop Printers

ZD621 Thermal Transfer 4 Print Width Premium Desktop Printer

Premium features, maximum performance and unmatched security to deliver years of high-quality printing in healthcare environments. The ZD621 brings premium print quality, features and reliability, ready for the needs of the healthcare sector of the future.

Ethernet203 DPI300 DPI
ZD621RZD621dZD621d-HCZD621tZD621t-HC
ZD621 Thermal Transfer 4 Print Width Premium Desktop Printer
Technical Specifications

Zebra ZD621 4-Inch Premium Desktop Printer

Print Method
Thermal transfer or direct thermal
Resolution
203 dpi / 8 dots per mm300 dpi / 12 dots per mm (optional)
Max Print Speed
8 in/203 mm per second (203 dpi); 6 in/152 mm per second (300 dpi)
Max Print Width
4.09 in/104 mm at 203 dpi; 4.27 in/108 mm at 300 dpi
Connectivity
Ethernet, Serial, USB 2.0, USB Host; optional 802.11ac Wi-Fi and Bluetooth 4.1
Operating System
Link-OS
Memory
512 MB flash; 256 MB SDRAM
Display
Optional 4.3-inch full-color touch LCD (480 x 272) with 3-button user interface
Dimensions
Direct thermal: 8.7 x 7.0 x 5.9 in (221 x 177 x 151 mm); Thermal transfer: 10.5 x 8.0 x 7.5 in (267 x 202 x 192 mm)
Weight
Direct thermal: 3.6 lb/1.6 kg; Thermal transfer: 5.5 lb/2.5 kg
Power
Auto-sensing 100-240 V AC, 50-60 Hz; ENERGY STAR certified; optional 2750 mAh battery
Total Configurations
36
Key Features

Healthcare and Standard Features

White color, preferred for healthcare environments

Healthcare-grade power supply with IEC 60601-1 certification

Easy-to-clean, disinfectant-ready plastics with a sealed button interface

UV-resistant housing that supports UV-light cleaning protocols

Print methods: thermal transfer or direct thermal, with ZPL and EPL programming languages

4.3-inch full-color touch LCD (480 x 272 resolution) with a 3-button user interface and 5 status icons

Ethernet, Serial, USB 2.0 and USB Host, plus a printer setup mobile app for Android and iOS over a Bluetooth Low Energy (BLE 5) connection

Real-time clock (RTC) and media tensioning for excellent print quality

OpenACCESS for easy media loading and double-wall frame construction

ENERGY STAR certified, with ZebraDesigner Essentials for simple label design

Overview

About the Zebra ZD621 4-Inch Desktop Printer

The Zebra ZD621 delivers premium features, maximum performance and unmatched security to provide years of high-quality printing in healthcare environments. Building on a proven, successful design, it is available in thermal transfer and direct thermal models and supports both ZPL and EPL programming languages with the Link-OS operating system.

The ZD621 offers premium print quality, features and reliability, ready for the needs of the healthcare sector of the future. It prints at 203 or 300 dpi at speeds up to 8 in/203 mm per second, with a 4.3-inch full-color touch LCD option, Ethernet, Serial, USB 2.0 and USB Host connectivity, and optional 802.11ac Wi-Fi and Bluetooth 4.1. Healthcare models add a white, disinfectant-ready chassis, UV-resistant housing and an IEC 60601-1 power supply.

As a Zebra partner, Barrdega supplies the full ZD621 lineup with expert configuration guidance — request a quote for project pricing.

Full Specifications

Zebra ZD621 Technical Specifications

Specification Detail
DimensionsDirect thermal: 8.7 in L x 7.0 in W x 5.9 in H (221 mm x 177 mm x 151 mm). Thermal transfer: 10.5 in L x 8.0 in W x 7.5 in H (267 mm x 202 mm x 192 mm)
WeightDirect thermal: 3.6 lb/1.6 kg. Thermal transfer: 5.5 lb/2.5 kg
Operating SystemLink-OS
Resolution203 dpi/8 dots per mm; 300 dpi/12 dots per mm (optional)
Memory512 MB flash memory; 256 MB SDRAM. 64 MB non-volatile memory available to the user; 8 MB SDRAM available to the user
Max Print Width4.09 in/104 mm at 203 dpi; 4.27 in/108 mm at 300 dpi
Max Print Speed8 in/203 mm per second (203 dpi); 6 in/152 mm per second (300 dpi)
Media SensorsFull-width movable reflective/black-mark sensor; multi-position transmissive/gap sensor
FirmwareZPL II; EPL 2; XML; ZBI; PDF Direct
Label LengthMinimum: 0.25 in/6.4 mm. Maximum: 39.0 in/991 mm
Media WidthDirect thermal: 0.585 in/15 mm to 4.25 in/108 mm. Thermal transfer: 0.585 in/15 mm to 4.65 in/118 mm
Media Roll SizeMaximum outer diameter: 5.00 in/127 mm. Core inner diameter: 0.5 in (12.7 mm) and 1.0 in (25.4 mm) standard; and 1.5 in (38.1 mm), 2.0 in (50.8 mm) and 3.0 in (76.2 mm) with optional adapters
Media Thickness0.003 in (0.08 mm) min.; 0.0075 in (0.19 mm) max. (tear-off mode only)
Media TypesRoll-fed or fanfold die-cut or continuous media with or without black mark, label or tag stock, continuous receipt paper, wristbands
Ribbon Outer Diameter2.6 in/66 mm (300 m); 1.34 in/34 mm (74 m)
Standard Ribbon Length984 ft (300 m); 243 ft (74 m)
Ribbon Ratio1:4 ribbon to media (300 m); 1:1 ribbon to media (74 m)
Ribbon Width1.33 in/33.8 mm - 4.3 in/109.2 mm
Ribbon Core Inner Diameter300-meter ribbon: 1 in/25.4 mm. 74-meter ribbon: 0.5 in/12.7 mm
Operating Temperature40 °F to 105 °F / 4.4 °C to 41 °C
Storage Temperature-40 °F to 140 °F / -40 °C to 60 °C
Operating Humidity10% to 90% non-condensing
Storage Humidity5% to 95% non-condensing
ElectricalAuto-sensing (PFC compliant) 100 to 240 V AC, 50 to 60 Hz; ENERGY STAR certified; Level VI energy efficiency certified; optional 2750 mAh battery; healthcare models include an IEC 60601-1 certified power supply
Media HandlingDispenser/peeler: peel and present labels with label-taken sensor (factory- or field-installable); cutter (factory- or field-installable)
Communications802.11ac Wi-Fi and Bluetooth 4.1 (dual-band radio), factory- or field-installable
BatteryPowers the printer to print at full speed through complete shifts; compatible with all connectivity and media-handling options
Carrying CaseCarrying case with shoulder strap and handles to transport the desktop printer and battery to the installation site
Standalone Keyboard DisplayZebra Keyboard Display Unit (ZKDU) for standalone printing solutions
Media Locking CabinetMechanical lock with two keys; Kensington lock slot; only available on the ZD621 direct thermal healthcare model
Enclosed Power SupplyIncluded accessory for a power supply that hides the cables
Barcode Ratios2:1 and 3:1
1D BarcodesCode 11, Code 39, Code 93, Code 128, ISBT-128, UPC-A, UPC-E, EAN-8, EAN-13, UPC and EAN with 2- or 5-digit extensions, Plessey, Postnet, Standard 2 of 5, Industrial 2 of 5, Interleaved 2 of 5, Logmars, MSI, Codabar and Planet Code
2D BarcodesCodablock, PDF417, Code 49, DataMatrix, MaxiCode, QR Code, MicroPDF, Aztec
Fonts and Graphics16 resident expandable ZPL II bitmap fonts, two resident scalable ZPL fonts, five resident expandable EPL2 fonts, native open-type font support and Unicode compatible. China units include the SimSun simplified Chinese font
Agency ApprovalsIEC 60950-1, IEC 62368-1, EN55022 Class B, EN55024, EN55035, EN61000-3-2, EN61000-3-3, FCC Class B, ICES-003, FCC 15.209; 15.247(d), IC RSS 247, EN 300 328, EN 301 893, EN 62311, cTUVus, CE Mark, VCCI, C-Tick, S-Mark, CCC, CU, BSMI, KCC, SABS, IN-Metro, BIS, NOM
EnvironmentalRoHS (Directive 2011/65/EU; Amendment 2015/863)
In the BoxPrinter, empty ribbon take-up cores (1 in and 0.5 in), 300 m third-party ribbon core adapters (2), AC power supply, power cord(s), USB cable, quick-start guide, regulatory guide. Empty take-up cores and core adapters are included only with ZD621 thermal transfer models
WarrantyZD600 Series printers are warranted against defects in workmanship and materials for a minimum of two (2) years from the date of shipment. Warranty varies by region
All Configurations

36 configurations

36 items
Part Number Model Description
ZD6A043-301F00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A042-301F00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A143-301F00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A142-30AFR2EZ ZD621R Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, ROW, RFID - UHF, Brazil Cord, Swiss Font, EZPL
ZD6A042-D01F00EZ ZD621d Direct Thermal Printer ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A142-301F00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A142-301FR2EZ ZD621R Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, ROW, RFID - UHF, US Cord, Swiss Font, EZPL
ZD6A142-D01F00EZ ZD621d Direct Thermal Printer ZD621; Color Touch LCD, 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A042-D2AF00EZ ZD621d Direct Thermal Printer ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Cutter, Brazil Cord, Swiss Font, EZPL
ZD6A043-D01F00EZ ZD621d Direct Thermal Printer ZD621; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A042-D21F00EZ ZD621d Direct Thermal Printer ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Cutter, US Cord, Swiss Font, EZPL
ZD6A042-D01R01EZ ZD621d Direct Thermal Printer ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, 802.11ax, BT5.3, USA/Canada, US Cord, Swiss Font, EZPL
ZD6A042-321F00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Cutter, US Cord, Swiss Font, EZPL
ZD6A142-D01R01EZ ZD621d Direct Thermal Printer ZD621; Color Touch LCD, 203 dpi, USB, USB Host, Ethernet, Serial, 802.11ax, BT5.3, USA/Canada, US Cord, Swiss Font, EZPL
ZD6A042-301R01EZ ZD621t Thermal Transfer Printer (74/300M) ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, 802.11ax, BT5.3, USA/Canada, US Cord, Swiss Font, EZPL
ZD6A043-301R01EZ ZD621t Thermal Transfer Printer (74/300M) ZD621; 300 dpi, USB, USB Host, Ethernet, Serial, 802.11ax, BT5.3, USA/Canada, US Cord, Swiss Font, EZPL
ZD6A143-301FR2EZ ZD621R Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, ROW, RFID - UHF, US Cord, Swiss Font, EZPL
ZD6AH43-301F00EZ ZD621t-HC Thermal Transfer Printer (74/300M) ZD621, Healthcare, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6AH42-D01F00EZ ZD621d-HC Direct Thermal Printer ZD621; Healthcare, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A142-311FR2EZ ZD621R Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, ROW, Dispenser (Peeler), RFID - UHF, US Cord, Swiss Font, EZPL
ZD6A042-D11F00EZ ZD621d Direct Thermal Printer ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Dispenser (Peeler), US Cord, Swiss Font, EZPL
ZD6A143-D01F00EZ ZD621d Direct Thermal Printer ZD621; Color Touch LCD, 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A143-D01R01EZ ZD621d Direct Thermal Printer ZD621; Color Touch LCD, 300 dpi, USB, USB Host, Ethernet, Serial, 802.11ax, BT5.2, USA/Canada, US Cord, Swiss Font, EZPL
ZD6A043-311F00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Dispenser (Peeler), US Cord, Swiss Font, EZPL
ZD6A042-30AF00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Brazil Cord, Swiss Font, EZPL
ZD6A043-321F00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Cutter, US Cord, Swiss Font, EZPL
ZD6A142-301RR1EZ ZD621t Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, 802.11ax, BT5.3, USA/Canada, RFID - UHF, US Cord, Swiss Font, EZPL
ZD6AH42-D01R01EZ ZD621d-HC Direct Thermal Printer ZD621; Healthcare, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, 802.11ax, BT5.2, USA/Canada, US Cord, Swiss Font, EZPL
ZD6A143-30EFR2EZ ZD621R Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, ROW, RFID - UHF, EU and UK Cords, Swiss Font, EZPL
ZD6AH42-301F00EZ ZD621t-HC Thermal Transfer Printer (74/300M) ZD621, Healthcare, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A142-321F00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Cutter, US Cord, Swiss Font, EZPL
ZD6AL42-D01F00EZ ZD621d-HC Direct Thermal Printer ZD621; Healthcare, Locking, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A042-311F00EZ ZD621t Thermal Transfer Printer (74/300M) ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Dispenser (Peeler), US Cord, Swiss Font, EZPL
ZD6AH43-D01F00EZ ZD621d-HC Direct Thermal Printer ZD621; Healthcare, Color Touch LCD; 300 dpi, USB, USB Host, Ethernet, Serial, BTLE5, US Cord, Swiss Font, EZPL
ZD6A042-D41F00EZ ZD621d Direct Thermal Printer ZD621; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, Linerless with Cutter and Label Taken Sensor, US Cord, Swiss Font, EZPL
ZD6A142-30EFR2EZ ZD621R Thermal Transfer Printer (74/300M) ZD621R, Color Touch LCD; 203 dpi, USB, USB Host, Ethernet, Serial, BTLE5, ROW, RFID - UHF, EU and UK Cords, Swiss Font, EZPL

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